BDBM50001514 1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione::CHEMBL24107

SMILES CCn1c(=O)n(C)c2nc[nH]c2c1=O

InChI Key InChIKey=KVSRUALMCYFLEP-UHFFFAOYSA-N

Data  9 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50001514   

TargetAdenosine receptor A1(GUINEA PIG)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50001514(1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  9.80E+3nMAssay Description:Affinity against adenosine A1 receptor in the brain membranes by the displacement of [3H]-CPX.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001514(1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  1.50E+4nMAssay Description:Ability to inhibit binding of 1 nM [3H]-cyclohexyladenosine to adenosine A1 receptor in rat cerebral cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001514(1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity at Adenosine A1 receptor in rat brain cortical membrane using [3H]-N6-R-phenylisopropyladenosine (R-PIA) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001514(1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione | CH...)
Affinity DataKi:  2.47E+4nMAssay Description:Binding affinity of specific [3H]-R-PIA binding to rat Adenosine A1 receptor in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed